2,7-diazaspiro[4.5]decan-1-one

2,7-diazaspiro[4.5]decan-1-one - Names and Identifiers

Name	tert-butyl 2,7-diazaspiro[4.5]decane-2-carboxylate
Synonyms	2-Boc-2,7-diazaspiro[4.5]... 2,7-Diazaspiro[4.5]decan-1-on 2,7-diazaspiro[4.5]decan-1-one 2-Boc-2,7-diazaspiro[4.5]decane 2-Boc-2,7-diazaspiro[4.5]decane oxalate tert-Butyl-2,7-diazaspiro[4.5]decan-2-carboxylate tert-butyl 2,7-diazaspiro[4.5]decane-2-carboxylate tert-butyl 2,7-diazaspiro[4,5]decane-2-carboxylate TERT-BUTYL 2,7-DIAZASPIRO[4.5]DECANE-2-CARBOXYLATE 2,7-Diazaspiro[4.5]decane-2-carboxylic acid tert-butyl ester 2,8-Diaza-Spiro[4.5]Decane-2-Carboxylic Acid Tert-Butyl Ester 2,7-Diazaspiro[4.5]decane-2-carboxylic acid, 1,1-diMethylethyl ester
CAS	852339-03-8 885268-42-8 887118-43-6
InChI	InChI=1/C8H14N2O/c11-7-8(3-5-10-7)2-1-4-9-6-8/h9H,1-6H2,(H,10,11)

2,7-diazaspiro[4.5]decan-1-one - Physico-chemical Properties

Molecular Formula	C13H24N2O2
Molar Mass	240.34
Density	1.07
Boling Point	337℃
Flash Point	158℃
Vapor Presure	2.27E-05mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.533

2,7-diazaspiro[4.5]decan-1-one - Risk and Safety

Risk Codes

52 - Harmful to aquatic organisms

2,7-diazaspiro[4.5]decan-1-one - Introduction

Nature:
-Appearance: tert-butyl 2,7-diazaspiro[4.5]decane-2-carboxylate is a colorless and transparent liquid.
-Molecular formula: C12H23N3O2
-Molecular weight: 241.33g/mol
-Melting point:-65 ℃
-Boiling point: 230 ℃
-Density: approx. 0.951g/cm³

Use:
- tert-butyl 2,7-diazaspiro[4.5]decane-2-carboxylate are mainly used as reagents and intermediates in organic synthesis.
-It can participate in a variety of organic reactions, such as esterification, reduction and oxidation of carbonyl compounds, etc. It also has applications in drug synthesis and the synthesis of chiral drugs.

Preparation Method:
- tert-butyl 2,7-diazaspiro[4.5] The preparation of decane-2-carboxylate can be achieved by a variety of methods. One of the commonly used methods is the reaction of 2,7-diazaspiro [4.5] decane-2-methanol with tert-butyric acid chloride to produce the corresponding esterification product. Thereafter, the target product is selectively tert-butyl-protected under appropriate conditions.

Safety Information:
- tert-butyl 2,7-diazaspiro[4.5]decane-2-carboxylate should avoid inhalation, contact with skin and eyes.
-Wear appropriate protective equipment such as goggles and gloves when using.
-It should be operated in a well-ventilated place and avoid contact with fire or high temperature.
-In case of inhalation or contact, immediately go to a fresh air or rinse with water and seek medical attention immediately.

Please note that before performing any laboratory operations, please make sure that you have the correct operating skills and safety knowledge, and follow the relevant safety operating procedures.

Last Update：2024-04-09 15:18:00